CAS NO: | 74058-71-2 |
包装 | 价格(元) |
10mg | 询价 |
50mg | 询价 |
100mg | 询价 |
Cas No. | 74058-71-2 |
别名 | N-苄基棕榈酰胺,N-Benzylhexadecanamide |
化学名 | N-(phenylmethyl)-hexadecanamide |
Canonical SMILES | O=C(CCCCCCCCCCCCCCC)NCC1=CC=CC=C1 |
分子式 | C23H39NO |
分子量 | 345.6 |
溶解度 | ≤2mg/ml in organic solvent ethanol |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | N-Benzylpalmitamide is an inhibitor of fatty acid amide hydrolase (FAAH) [1]. The fatty acid amide hydrolase (FAAH) is a mammalian integral membrane enzyme responsible for the hydrolysis of anandamide, an endocannabinoid. The FAAH is involved in degrading the fatty acid amide family of endogenous signaling lipids, including the endogenous cannabinoid anandamide and the sleep-inducing substance oleamide. FAAH belongs to is a member of amidase signature (AS) family. The FAAH integrates into cell membranes and terminates fatty acid amide signaling in vivo [2]. Genetic mutations in FAAH may constitute important risk factors for problem drug use and support a potential link between functional abnormalities in the endogenous cannabinoid system and drug abuse and dependence [3]. N-Benzylpalmitamide was a long-chain fatty acid amide isolated from the maca (L. meyenii) plant and was structurally related to cannabinoids. N-Benzylpalmitamide was a moderate inhibitor of FAAH and inhibited 44% activity of FAAH at 500 μM [1]. References: |
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