Terazosin hydrochloride 是一种喹唑啉衍生物，是一种竞争性且具有口服活性的 α1-adrenoceptor 拮抗剂。
| Cas No. | 63074-08-8 |
| 别名 | 盐酸特拉唑嗪 |
| Canonical SMILES | Cl.COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1CCCO1 |
| 分子式 | C19H25N5O4.HCl |
| 分子量 | 423.9 |
| 溶解度 | DMSO: 0.1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo. Kyncl (1986) Pharmacology of tera. Am.J.Med. 80 12 PMID:2872801 |Hancock et al (1995) Actions of tera. and its enantiomers at subtypes of α1- and α2-adrenoceptors in vitro. J.Recept.Signal Transduct.Res. 15 863 PMID:8673721 |Maruyama et al (1994) Comparison of displacemental potencies of tera. enantiomers for α1-adrenoceptor subtypes. Biol.Pharm.Bull. 17 1126 PMID:7820122 |
