| CAS NO: | 58569-55-4 |
| 包装 | 价格(元) |
| 10mM (in 1mL Water) | 询价 |
| 25mg | 询价 |
| 50mg | 询价 |
| 100mg | 询价 |
| Cas No. | 58569-55-4 |
| 别名 | 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin |
| Canonical SMILES | Tyr-Gly-Gly-Phe-Met |
| 分子式 | C27H35N5O7S |
| 分子量 | 573.66 |
| 溶解度 | DMSO : ≥ 40 mg/mL (69.73 mM);Water : 6.67 mg/mL (11.63 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor. Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1]. [1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9. |
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