里拉胺（盐酸盐）是一种从松树皮中提取的三环二萜分子。
| Cas No. | 16496-99-4 |
| 别名 | 脱氢松香胺盐酸盐 |
| 化学名 | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride |
| Canonical SMILES | CC(C)C(C=C1)=CC2=C1[C@]3(C)[C@](CC2)([H])[C@@](CN)(C)CCC3.Cl |
| 分子式 | C20H31N.HCl |
| 分子量 | 321.9 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:2): .15 mg/ml,Ethanol: 20 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 of 9.5 uM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources. |
