| 产品描述 | Cicloprofen is a non-steroidal anti-inflammatory drug (NSAID).1,2It inhibits histamine release induced by ragweed, A23187 , or concanavalin A in isolated human leukocytes when used at a concentration of 0.5 mM.1Cicloprofen inhibits carrageenan-induced paw edema in rats (ED50= 67 mg/kg).2 1.Hearn, T., and Wojnar, R.J.Characterization of augmentation of allergic and non-allergic histamine release by non-steroidal anti-inflammatory/analgesic agentsAgents Actions11(4)352-360(1981)
2.Stiller, E.T., Diassi, P.A., Gerschutz, D., et al.Synthesis and antiinflammatory activities of α-methylfluorene-2-acetic acid and related compoundsJ. Med. Chem.15(10)1029-1032(1972) |
