| CAS NO: | 105-20-4 |
| 包装 | 价格(元) |
| 10mg | 询价 |
| 50mg | 询价 |
| Cas No. | 105-20-4 |
| 别名 | 倍他唑,Ametazole |
| Canonical SMILES | NCCC1=NNC=C1 |
| 分子式 | C5H9N3 |
| 分子量 | 111.15 |
| 溶解度 | DMSO: 250 mg/mL (2249.21 mM) |
| 储存条件 | 4℃, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. Betazole induces gastric acid secretion and causes an immediate and significant increase in common bile duct pressure. Betazole is used as a diagnostic agent known as histalog for investigating gastric acid secretory capacity[1][2][3]. Betazole (Ametazole) is a weak histamine agonist with relative selectivity towards H2 receptors and only minimal H1 activity. Betazole induces gastric inhibitory polypeptide (GIP) secretion[1]. [1]. Maples MD, Effects of betazole hydrochloride and cimetidine on common bile pressure and duodenal myoelectric activity in the dog. Am Surg. 1981;47(12):519-521. [2]. Spitz IM, Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism. 1982;31(4):380-382. [3]. CLAYMAN CB,. A simple oral gastric secretory stimulant (betazole hydrochloride). JAMA. 1961;175:908-909. |
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