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(-)-α-Pinene
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-α-Pinene图片
CAS NO:7785-26-4

(-)-α-Pinene 是一种单萜类化合物,通过在 BZD 结合位点作为部分调节剂与 GABAA-苯二氮卓 (BZD) 受体直接结合,显示出增强睡眠的特性。
Cas No.7785-26-4
别名β-蒎烯; (-)-β-Pinene
Canonical SMILESCC1(C)[C@@]2([H])CC=C(C)[C@]1([H])C2
分子式C10H16
分子量136.23
溶解度DMSO: 60 mg/mL (440.43 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site[1].

(-)-α-pinene enhances the quantity of non-rapid eye movement sleep (NREMS) without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directly binding to the BZD binding site of GABAA receptor[1].

[1]. Yang H, et al. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Micethrough GABAA-benzodiazepine Receptors.

 
 
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