MRGPRX1 agonist 1 是一种高效的 Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1) 的激动剂，EC50 值为 50 nM，对 MRGPRC11 无活性。MRGPRC11 具有镇痛活性。
| Cas No. | 2377379-39-8 |
| 分子式 | C23H21N3O4S |
| 分子量 | 435.5 |
| 溶解度 | DMSO : 130 mg/mL (298.51 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1]. [1]. PrchalovÁ E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641. |
