MuRF1-IN-1 是一种 MuRF1 抑制剂，可减轻心脏恶病质中的骨骼肌萎缩和功能障碍。
| Cas No. | 445222-91-3 |
| 别名 | 2-氨基-1'-甲基-2',5--二氧代-5,6,7,8-四氢螺[苯并吡喃-4,3'-吲哚啉]-3-甲腈 |
| 分子式 | C18H15N3O3 |
| 分子量 | 321.33 |
| 溶解度 | DMSO : 125 mg/mL (389.01 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MuRF1-IN-1 is a muscle ring finger 1 (MuRF1) inhibitor that attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia[1]. [1]. Bowen TS, Adams V, Werner S, et al. Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):939-953. |
