NRX-1933 是一种 β-catenin:β-TrCP 相互作用增强剂,用于开发小分子降解物。
Cas No. | 2763260-30-4 |
分子式 | C14H9F3N6O2 |
分子量 | 350.26 |
溶解度 | DMSO : 83.33 mg/mL (237.91 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NRX-1933 is a β-catenin:β-TrCP interaction enhancer for the development of small molecule degraders. [1]. Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402. |