NSC2805 是一种 WWP1 泛素连接酶抑制剂，能显著抑制 WWP2 活性，其 IC50值为 0.38 μM。NSC2805 可用于癌症的研究。
| Cas No. | 4371-34-0 |
| 分子式 | C14H14O4 |
| 分子量 | 246.26 |
| 储存条件 | 4°C, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | NSC2805 is aWWP2 ubiquitin ligaseinhibitor that can significant inhibit WWP2 activity with anIC50of 0.38 μM. NSC2805 can be used for the research of cancer[1]. NSC2805 has WWP2 inhibitory activity with anIC50of 0.38 μM[1].
NSC2805 shows a significant reduction in activity for all three proteins (WWP2, WWP1 and Nedd4)[1].
NSC2805 can robustly inhibit WWP2-dependent PTEN ubiquitination[1]. |
