O-GlcNAcase-IN-1 是一种新颖且有效的 OGA 抑制剂,其 IC50 值为 46 nM。
Cas No. | 2757254-99-0 |
别名 | O-GlcNAcase-IN-1 |
分子式 | C15H22N6 |
分子量 | 286.38 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | O-GlcNAcase-IN-1 is a potent and novel OGA inhibitor with an IC50 value of 46 nM. [1]. Tawada M, et al. Discovery of a Novel and Brain-Penetrant O-GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead Optimization. J Med Chem. 2021 Jan 28;64(2):1103-1115. |