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MCL-1/BCL-2-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MCL-1/BCL-2-IN-2图片
CAS NO:2163793-44-8

MCL-1/BCL-2-IN-2 (Compound 6) 是一种有效的选择性 Mcl-1 和 Bcl-2 抑制剂。
Cas No.2163793-44-8
Canonical SMILESO=C1N(CCN)C(C2=CC=C(SC3=CC=C(Br)C=C3)C4=CC=CC1=C24)=O
分子式C20H15BrN2O2S
分子量427.31
溶解度DMSO: 5 mg/mL (11.70 mM; ultrasonic and warming and heat to 60℃)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

 
 
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