Pemigatinib是一种选择性的FGFR抑制剂,目前处于开发治疗胆管癌患者。
Cas No. | 1513857-77-6 |
别名 | 培米加替尼,INCB054828 |
Canonical SMILES | CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4 |
分子式 | C24H27F2N5O4 |
分子量 | 487.5 |
溶解度 | DMSO : 41.67 mg/mL (85.48 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma. [1]. Arudra K, et al. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct;45(10):786-790. |