AGL-2263是胰岛素受体(IR)的一个阻断剂。
Cell experiment: | Trophoblast cells are prepared from normal or GDM placentas. They are incubated in the presence of stimulants, insulin (100 nM) or both insulin and AGL-2263 (AGL, 5 μM) IR blocker, together for 24 hr[1]. |
| 产品描述 | AGL-2263 is an insulin receptor (IR) blocker. AGL-2263 is an insulin receptor (IR) blocker[1]. [1]. Li Y, et al. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5697-705. |
