FLT3-IN-2是一种IC50<1 μM的FLT3抑制剂，详细信息参见WO 2012158957 A2和WO 2007013896。
| Cas No. | 923562-23-6 |
| Canonical SMILES | FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=C1)(F)F |
| 分子式 | C21H16ClF3N4 |
| 分子量 | 416.83 |
| 溶解度 | DMSO : ≥ 30 mg/mL (71.97 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | FLT3-IN-2 is a FLT3 inhibitor with IC50 of< 1 uM, detailed information refer to WO 2012158957 A2 and WO 2007013896. References:
[1]. Zhang, Chao, et al. Kinase modulation for the treatment of leukemias. From PCT Int. Appl. (2012), WO 2012158957 A2 20121122.
[2]. Zhang Chao, et al. 7-Azaindole derivatives and their preparation, pharmaceutical compositions and use for modulating c-kit and c-fms activity. From PCT Int. Appl. (2007), WO 2007013896 A2 20070201. |
