氨苯砜 D8（4,4'-二氨基二苯砜 D8）是一种氘标记的氨苯砜。
| Cas No. | 557794-38-4 |
| 别名 | 氘代氨苯砜,4,4′-Diaminodiphenyl sulfone-d8; DDS-d8 |
| Canonical SMILES | NC1=C([2H])C([2H])=C(S(C2=C([2H])C([2H])=C(N)C([2H])=C2[2H])(=O)=O)C([2H])=C1[2H] |
| 分子式 | C12H4D8N2O2S |
| 分子量 | 256.3 |
| 溶解度 | DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dapsone-d8is intended for use as an internal standard for the quantification of dapsone by GC- or LC-MS. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders.1Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved. 1.Bonde, S.L., Bhadane, R.P., Gaikwad, A., et al.Simultaneous determination of Dapsone and its major metabolite N-acetyl Dapsone by LC-MS/MS methodInt. J. Pharm. Pharm. Sci.5(Suppl 3)441-446(2013) |
