Bromhexine HCl 是一种有效且特异性的 TMPRSS2 蛋白酶抑制剂，IC50 为 0.75 μM。
| Cas No. | 611-75-6 |
| 别名 | 盐酸溴己新 |
| 化学名 | 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;hydrochloride |
| Canonical SMILES | CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2.Cl |
| 分子式 | C14H20Br2N2.HCl |
| 分子量 | 412.59 |
| 溶解度 | ≥ 8.3mg/mL in DMSO with gentle warming |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm.Target: OthersBromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties. Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport". From Wikipedia. [1] References:
[1]. http://en.wikipedia.org/wiki/Bromhexine |
