| CAS NO: | 1177279-49-0 |
| Cas No. | 1177279-49-0 |
| 别名 | WEB 1881 FU hydrochloride |
| Canonical SMILES | O=C1N(CC2=CC=CC=C2)CC(CN)C1.[H]Cl |
| 分子式 | C12H17ClN2O |
| 分子量 | 240.73 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃, protect from light, sealed storage, away from moisture |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1]. Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms[2]. Animal Model: Male Wistar rats weighing 200-250 g[2]. [1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26. |
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