| 包装 | 价格(元) |
| 25 µg | 询价 |
| 50 µg | 询价 |
| 100 µg | 询价 |
| Canonical SMILES | O[C@@H](COP(O)(O)=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O |
| 分子式 | C19H30D9O7P |
| 分子量 | 419.5 |
| 溶解度 | Ethanol: 10mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 1-Palmitoyl-d9lysophosphatidic acid (1-palmitoyl-d9LPA) is intended for use as an internal standard for the quantification of 1-palmitoyl LPA by GC- or LC-MS. 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid at thesn-1 position. It induces reporter gene expression in PC12 cells expressing human lysophosphatidic acid receptor 4 (LPA4) when used at concentrations ranging from 0.01 to 10 µM.11-Palmitoyl LPA (12-300 µM) induces aggregation of isolated human platelets, an effect that can be reversed by prostaglandin E1, theophylline , or EDTA.2It also binds to calcium and magnesium and enhances the activity of ampicillin , piperacillin , and ceftazidime againstP. aeruginosaisolates from patients with cystic fibrosis.3 1.Noguchi, K., Ishii, S., and Shimizu, T.Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg familyJ. Biol. Chem.278(28)25600-25606(2003) 2.Gerrard, J.M., Kindom, S.E., Peterson, D.A., et al.Lysophosphatidic acids. Influence on platelet aggregation and intracellular calcium fluxAm. J. Pathol.96(2)423-438(1979) 3.Krogfelt, K.A., Utley, M., Krivan, H.C., et al.Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosaJ. Antimicrob. Chemother.46(3)377-384(2000) |
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