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Ralfinamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ralfinamide图片
CAS NO:133865-88-0

Ralfinamide (FCE-26742A) 是一种口服可利用,来源于 α-aminoamide 的钠离子通道阻滞剂, 具有镇痛作用。
Cas No.133865-88-0
别名(S)-2-[[4-[(2-氟苄基)氧基]苄基]氨基]丙酰胺,FCE-26742A
Canonical SMILESC[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O
分子式C17H19FN2O2
分子量302.34
溶解度DMSO: ≥ 125 mg/mL (413.44 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ralfinamide (FCE-26742A) is an orally available Na(+) channel blocker derived from α-aminoamide, with function of suppressing pain[1]. Sodium Channel[1]

[1]. Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139(2):293-305. [2]. Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.

 
 
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