DSP-2230 是选择性的 Nav1.7/Nav1.8 通道阻断剂。
| Cas No. | 1233231-30-5 |
| Canonical SMILES | C[C@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C4CCC4)C(N)=O |
| 分子式 | C20H20F3N5O2 |
| 分子量 | 419.4 |
| 溶解度 | DMSO: 125 mg/mL (298.04 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | DSP-2230 is a selective Nav1.7/Nav1.8 blocker[1][2].
Nav1.7/Nav1.8[1] [1]. Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6.
[2]. Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels. |
