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Dianicline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dianicline图片
CAS NO:292634-27-6

Dianicline是一种α4β2烟碱型乙酰胆碱受体部分激动剂,一类包括伐尼克兰和金雀花碱的戒烟药物。
Cas No.292634-27-6
Canonical SMILES[H][C@]1(CC[N@](CC2)C3)[C@]32CC4=NC=CC=C4O1
分子式C13H16N2O
分子量216.28
溶解度DMSO: 25 mg/mL (86.45 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. Dianicline increases cessation rates in a dose-dependent manner[1].

[1]. Tonstad S, et al. Dianicline, a novel α4β2 nicotinic acetylcholine receptor partial agonist, for smoking cessation: a randomized placebo-controlled clinical trial. Nicotine Tob Res. 2011 Jan;13(1):1-6.

 
 
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