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BTdCPU
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BTdCPU图片
CAS NO:1257423-87-2

BTdCPU 是有效的血红素调节的 eIF2α 激酶 (HRI) 激活剂。BTdCPU 促进耐药细胞中 eIF2α 磷酸化并诱导凋亡。
Cas No.1257423-87-2
Canonical SMILESO=C(NC1=CC=C2N=NSC2=C1)NC3=CC=C(C(Cl)=C3)Cl
分子式C13H8Cl2N4OS
分子量339.2
溶解度DMSO: ≥ 250 mg/mL (737.03 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BTdCPU is a potent heme-regulated eIF2α kinase (HRI) activator. BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell[1].

[1]. Burwick N, et al. The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. Leuk Res. 2017 Apr;55:23-32.

 
 
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