Ethoxysanguinarine 是主要存在龙葵中的一种 benzophenanthridine 生物碱天然产物。Ethoxysanguinarine 通过抑制蛋白磷酸酶 2A (CIP2A)，抑制结直肠癌细胞的活力，诱导细胞凋亡。
| Cas No. | 28342-31-6 |
| 别名 | 乙氧基血根碱 |
| Canonical SMILES | CN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C6=C(OCO6)C=C5)C1OCC |
| 分子式 | C22H19NO5 |
| 分子量 | 377.39 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A)[1]. [1]. Jin L, et al. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A. Int J Oncol. 2018 Mar 16. |
