An internal standard for the quantification of cotinine
| Cas No. | 110952-70-0 |
| 别名 | 氘代甲基可替宁,(±)-Cotinine-d3; (Rac)-NIH-10498-d3 |
| Canonical SMILES | O=C(N1C([2H])([2H])[2H])CCC1C2=CC=CN=C2 |
| 分子式 | C10H9D3N2O |
| 分子量 | 179.2 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (±)-Cotinine-d3is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine .1,2It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.2 1.StÅlhandske, T.The metabolism of nicotine and cotinine by a mouse liver preparationActa. Physiol. Scand.78(2)236-248(1970)
2.Murphy, S.E., Link, C.A., Jensen, J., et al.A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokersCancer Epidemiology, Biomarkers & Prevention13(10)1617-1623(2004) |
