Estramustine磷酸钠盐是抗微管蛋白化疗试剂。
| Cas No. | 52205-73-9 |
| 别名 | 雌莫司汀磷酸钠 |
| Canonical SMILES | [O-]P([O-])(O[C@H]1CC[C@@]2([H])[C@@]3([H])[C@](C(C=CC(OC(N(CCCl)CCCl)=O)=C4)=C4CC3)([H])CC[C@@]21C)=O.[Na+].[Na+] |
| 分子式 | C23H30Cl2NNa2O6P |
| 分子量 | 564.35 |
| 溶解度 | Water : 62.5 mg/mL (110.75 mM);DMSO : 5 mg/mL (8.86 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Estramustine phosphate sodium is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle. [1]. Perry CM, et al. Estramustine phosphate sodium. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer. Drugs Aging. 1995 Jul;7(1):49-74. [2]. Bergenheim AT, et al. Pharmacokinetics and pharmacodynamics of estramustine phosphate. Clin Pharmacokinet. 1998 Feb;34(2):163-72. [3]. Dene Simpson, et al. Estramustine Phosphate Sodium. American Journal of Cancer 2 (5):373-390. |
