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[Sar9,Met(O2)11]-Substance P TFA
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
[Sar9,Met(O2)11]-Substance P TFA图片

[Sar9,Met(O2)11]-Substance P TFA 是一种选择性的速激肽 NK1 受体激动剂。
分子式C66H101N18F3O17S
分子量1507.68
溶解度Water: 100 mg/mL (66.33 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.

[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].

[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.

 
 
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