SB 258719 是一个有选择性的 5-HT7 受体拮抗剂，其 pKi 值为 7.5。
| Cas No. | 195199-95-2 |
| Canonical SMILES | O=S(C1=CC=CC(C)=C1)(N(C)[C@H](C)CCN2CCC(C)CC2)=O |
| 分子式 | C18H30N2O2S |
| 分子量 | 338.51 |
| 溶解度 | DMSO: 250 mg/mL (738.53 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SB 258719 is a selective 5-HT7 receptor antagonist with a pKi of 7.5.
pKi: 7.5 (5-HT7 receptor) [1]. Thomas DR, et al. Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719. Br J Pharmacol. 1998 Jul;124(6):1300-6. |
