| CAS NO: | 2411382-24-4 |
| 包装 | 价格(元) |
| 500 μg | 询价 |
| 1mg | 询价 |
| 5mg | 询价 |
| Cas No. | 2411382-24-4 |
| Canonical SMILES | O=C(C1=CN(C2=NC=CN=C2)N=C1OC)NC3=CC=CC(C4=NN=CN4C(C)C)=N3 |
| 分子式 | C19H19N9O2 |
| 分子量 | 405.4 |
| 溶解度 | Chloroform: 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CAY10756 is a brain-penetrant inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC50= 21 nM).1It inhibits autophosphorylation of ASK1 in HEK293T cells (IC50= 138 nM). 1.Xin, Z., Himmelbauer, K., Jones, J.H., et al.Discovery of CNS-penetrant apoptosis signal-regulating kinase 1 (ASK1) inhibitorsACS Med. Chem. Lett.11(4)485-490(2020) |
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