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2-(Isopentylamino)naphthalene-1,4-dione
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-(Isopentylamino)naphthalene-1,4-dione图片
CAS NO:1607447-79-9
包装与价格：
包装价格(元)
1mg询价
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25mg询价

A vitamin K analog
Cas No.1607447-79-9
Canonical SMILESO=C1C(NCCC(C)C)=CC(C2=CC=CC=C21)=O
分子式C15H17NO2
分子量243.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).

1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizuresJ. Med. Chem.63(11)5865-5878(2020)

 
 
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