RY785 是一种有效的选择性电压门控钾 (KV2) 通道抑制剂，对 KV2.2 的 IC50 为 0.05 μM。
| Cas No. | 1393748-80-5 |
| Canonical SMILES | COC1=CC=CC(CC(C(NC2=CC(N=C(C3=CSC=N3)N4)=C4C=C2)=O)C)=C1 |
| 分子式 | C21H20N4O2S |
| 分子量 | 392.5 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 15 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 µM) that does not affect Cav2 calcium channels. It displays over 100-fold selectivity for Kv2.1 over Cav1.2 (IC50 = 17 µM). |
