Fura-2(钾盐)是一种缩放荧光染料,可用于细胞内钙成像,Kd 值为 140 nM。
Cas No. | 113694-64-7 |
别名 | 2-[6-[双(羧甲基)氨基]-5-[2-[2-[双(羧甲基)氨基]-5-甲基苯氧基]乙氧基]-2-苯并呋喃基]-5-恶唑羧酸五钾盐 |
化学名 | 2-[6-[bis(carboxymethyl)amino]-5-[2-[2-[bis(carboxymethyl)amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid, pentapotassium salt |
Canonical SMILES | [O-]C(CN(C1=CC2=C(C=C(C3=NC=C(C([O-])=O)O3)O2)C=C1OCCOC(C=C(C)C=C4)=C4N(CC([O-])=O)CC([O-])=O)CC([O-])=O)=O.[K+].[K+].[K+].[K+].[K+] |
分子式 | C29H22N3O14•5K |
分子量 | 832 |
溶解度 | Soluble in water |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. [1] It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells. Reference: [1]. Kong, S.K., and Lee, C.Y. The use of fura 2 for measurement of free calcium concentration. Biochem. Mol. Biol. Ed. 23(2), 97-98 (1995). |