Britannilactone (Desacetylinulicin) (Desacetylinulicin) 是英国旋花干花的甲醇提取物。
Cas No. | 33620-72-3 |
别名 | 旋覆花内酯,Desacetylinulicin |
Canonical SMILES | O[C@H]1[C@@](C2=C)([H])[C@@](OC2=O)([H])CC(C)=C1[C@@H](C)CCCO |
分子式 | C15H22O4 |
分子量 | 266.33 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Britannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L.IC50 value:Target:A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1]. [1]. Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74. |