Butin是从黄檀的心材中分离出的主要的一种生物活性黄酮类化合物，具有很强的抗氧化、抗血小板和抗炎活性。在大鼠中，Butin能显著减轻心肌梗死现象，改善心脏功能，预防糖尿病引起的心脏氧化损伤。
| Cas No. | 21913-99-5 |
| 别名 | 紫铆亭 |
| Canonical SMILES | O=C1CC(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC=C13 |
| 分子式 | C15H12O5 |
| 分子量 | 272.25 |
| 溶解度 | DMSO: 41.67 mg/mL (153.06 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat[1][2]. [1]. Duan J, et al. Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway. Sci Rep. 2017 Jan 27;7:41491.
[2]. Li P, et al. Butin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage by Anti Inflammatory Pathway. Transl Neurosci. 2018 May 8;9:7-12. |
