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Byakangelicin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Byakangelicin图片
CAS NO:482-25-7
包装:20mg
市场价:3339元

Byakangelicin 是在当归根中发现的一种活性化合物，可作为调节剂来改善大脑中多种活性化合物（Umb、Cur 和 Dox）的积累并增强治疗效果。
Cas No.482-25-7
别名白当归素
化学名9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxyfuro[3,2-g]chromen-7-one
Canonical SMILESCC(C)(C(COC1=C2C(=C(C3=C1OC(=O)C=C3)OC)C=CO2)O)O
分子式C17H18O7
分子量334.11
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects[1]. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones[2].

References:
[1]. Kang YY, et al. Byakangelicin as a modulator for improved distribution and bioactivity of natural compounds and synthetic drugs in the brain. Phytomedicine. 2019 May 17;62:152963.
[2]. Yang J, et al. Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes. Br J Pharmacol. 2011 Jan;162(2):441-51.

 
 
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