Phytohemagglutinin (PHA) 是一种凝集素，来自红芸豆，它与 T 细胞膜结合并刺激代谢活动，细胞分裂，参与炎症通路。Phytohemagglutinin (PHA) 通过增加促凋亡蛋白 Bax 和激活 caspases-3 诱导细胞凋亡。
| Cas No. | 9008-97-3 |
| 别名 | 植物血凝素; PHA-M |
| Canonical SMILES | [Phytohemagglutinin] |
| 溶解度 | Water : 50 mg/mL |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Phytohemagglutinin (PHA) is a lectin, obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways. Phytohemagglutinin (PHA) induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3[1][2][3]. [1]. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903.
[2]. Merlo JL, et al. Food Restriction Affects Inflammatory Response and Nutritional State in Tuco-tucos (Ctenomys talarum). J Exp Zool A Ecol Genet Physiol. 2016 Dec;325(10):675-687.
[3]. Kochubei TO, et al. Isolectins of phytohemagglutinin are able to induce apoptosis in HEp-2 carcinoma cells in vitro. Exp Oncol. 2015 Jun;37(2):116-9. |
