3-O-Methylquercetin(3-MQ)是来自植物Rhamnusnakaharai的主要成分,可抑制总cAMP和cGMP-phosphodiesterase(PDE)。3-O-Methylquercetin(3-MQ)对PDE1、PDE5、PDE和PDE4的IC50值分别为31.9μM、86.9μM、18.6μM和1.6μM。
Cas No. | 1486-70-0 |
别名 | 3-O-甲基槲皮素 |
Canonical SMILES | O=C1C(OC)=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
分子式 | C16H12O7 |
分子量 | 316.26 |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM, 86.9 μM, 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1]. [1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5. |