(S)-C33 是一种有效的选择性 PDE9 (phosphodiesterase-9) 抑制剂，IC50 为 11 nM。
| Cas No. | 2066488-39-7 |
| Canonical SMILES | C[C@@H](C1=CC=C(C=C1)Cl)NC2=NC(C3=C(N(C4CCCC4)N=C3)N2)=O |
| 分子式 | C18H20ClN5O |
| 分子量 | 357.84 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Potent PDE9 inhibitor (IC50 = 11 nM). Huang et al (2015) Structural asymmetry of phosphodiesterase-9A and a unique pocket for selective binding of a potent enantiomeric inhibitor. Mol.Pharmacol. 88 836 PMID:26316540 |
