Nucleoside-Analog-1是抗病毒核苷R1479的类似物,用于HCV看病毒核苷类似物的合成。
Cas No. | 876707-99-2 |
Canonical SMILES | O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C=C3)[C@H]1OC2=NC3=O |
分子式 | C9H9N5O5 |
分子量 | 267.2 |
溶解度 | Water : 20 mg/mL (74.85 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Nucleoside-Analog-1 is a 4′-Azidocytidine analogue against Hepatitis C virus replication. [1]. Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23. [2]. Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine. J Med Chem. 2009 May 14;52(9):2971-8. |