PROTACCDK9Degrader-1是一种有选择性的CDK9降解剂。
| Cas No. | 2118356-96-8 |
| 别名 | N-(5-环丁基-1H-吡唑-3-基)-2-(4-((5-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧代异吲哚啉-4-基)氧基)戊基)氧基)苯基)乙酰胺 |
| Canonical SMILES | O=C(CC1=CC=C(OCCCCCOC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O)C=C1)NC5=CC(C6CCC6)=NN5 |
| 分子式 | C33H35N5O7 |
| 分子量 | 613.66 |
| 溶解度 | DMSO : ≥ 104 mg/mL (169.47 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PROTAC CDK9 Degrader-1 is a selective CDK9 degrader. [1]. Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580. |
