Benzothiohydrazide是抗结核药物Isoniazid的一种类似物，具有抗结核活性，对M.tuberculosis野生型和临床突变型(IC1和IC2)的MIC分别为132μM和264μM。
| Cas No. | 20605-40-7 |
| Canonical SMILES | NNC(C1=CC=CC=C1)=S |
| 分子式 | C7H8N2S |
| 分子量 | 152.22 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Benzothiohydrazide is an analogue of anti-tubercular agent Isoniazid. Benzothiohydrazide exhibits anti-tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2)[1]. [1]. J. Laborde, et al. Synthesis, oxidation potential and anti-mycobacterial activity of isoniazid and analogues: insights into the molecular isoniazid activation mechanism. ChemistrySelect, 1(2), 172-179. |
