Pyraclostrobin 是一种球果苷杀菌剂 (fungicide)，可抑制真菌和哺乳动物细胞的线粒体复合物 III (mitochondrial complex III)。Pyraclostrobin 可诱导 3T3-L1 细胞内甘油三酯的积累。
| Cas No. | 175013-18-0 |
| 别名 | 吡唑醚菌酯 |
| Canonical SMILES | COC(N(C1=C(C=CC=C1)COC2=NN(C3=CC=C(Cl)C=C3)C=C2)OC)=O |
| 分子式 | C19H18ClN3O4 |
| 分子量 | 387.82 |
| 溶解度 | DMSO: 250 mg/mL (644.63 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pyraclostrobin is a strobilurin fungicide that inhibits mitochondrial complex III of fungal and mammalian cells. Pyraclostrobin induces triglyceride accumulation and triglyceride accumulation in 3T3-L1 cells. [1]. Anthony L Luz,et al. The High-Production Volume Fungicide Pyraclostrobin Induces Triglyceride Accumulation Associated With Mitochondrial Dysfunction, and Promotes Adipocyte Differentiation Independent of PPARγ Activation, in 3T3-L1 Cells. 2018 Jan 15;393:150-159.
[2]. Alexander H Tuttle, et al.Choice of Vehicle Affects Pyraclostrobin Toxicity in Mice.Chemosphere. 2019 Mar;218:501-506. |
