ABMA 是一种细胞内毒素和病原体的广谱抑制剂。ABMA 有效地保护细胞免受各种毒素和病原体的侵害，包括病毒，细胞内细菌和寄生虫。ABMA 选择性作用于宿主细胞晚期内体，而不是针对毒素或病原体本身，具有广谱抗感染活性。
| Cas No. | 332108-65-3 |
| Canonical SMILES | COC1=CC=C(Br)C=C1CNC2(C3)CC4CC3CC(C4)C2 |
| 分子式 | C18H24BrNO |
| 分子量 | 350.29 |
| 溶解度 | DMSO: 125 mg/mL (356.85 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity[1][2]. [1]. Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.
[2]. Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10(8):1140-1147. |
