Ceftezole sodium (CTZ sodium) 是一种广谱 cephem 抗生素，具有抑制多种革兰氏阳性菌和革兰氏阴性菌活性。Ceftezole sodium (CTZ sodium) 是一种有效的 alpha-glucosidase 抑制剂，具有体内抗糖尿病活性。
| Cas No. | 41136-22-5 |
| 别名 | 头孢替唑钠; CTZ sodium |
| Canonical SMILES | O=C(C(N12)=C(CSC3=NN=CS3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O.[Na+] |
| 分子式 | C13H12N8NaO4S3+ |
| 分子量 | 463.47 |
| 溶解度 | Water: 250 mg/mL (540.59 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ceftezole sodium (CTZ sodium) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole sodium (CTZ sodium) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2]. [1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83.
[2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82. |
