Abrocitinib(PF-04965842)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS: | 1622902-68-4 |
分子式: | C14H21N5O2S |
分子量: | 323.41 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Inflammation/Immunology |
Target: | JAK1:29 nM (IC50);Tyk2:1253 nM (IC50) |
描述: | Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on |