JNJ-10229570
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| CAS: | 524923-88-4 |
| 分子式: | C22H19N3O2S |
| 分子量: | 389.47 |
| 纯度: | >98% |
| 溶解性: | DMSO : 62.5 mg/mL (160.47 mM; Need ultrasonic) |
| 存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域: | Endocrinology |
| Target: | IC50: 270 nM (human MC1R), 200 nM (human MC5R) |
| 描述: | JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-1022 |