CAS: | 896466-04-9 |
分子式: | C19H23N7O2 |
分子量: | 381.43 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 1.2 nM (JAK2), 1.1 nM (JAK3), 3 nM (Aurora A), 3 nM (Aurora B)[1] |
描述: | AT9283 is a multi-targeted inhibitor with IC50 of 1.2 nM, 1.1 nM for JAK2 and JAK3, respectively, and is also potent to Aurora A, Aurora B and Abl(T315I). |