A polyketide with immunosuppressant activity
| Cas No. | 571194-06-4 |
| Canonical SMILES | COC([C@]12[C@]3([H])[C@](C4=C(OC5=CC(C)=CC(O)=C5C4=O)C[C@@]3([H])[C@](O)(O2)C(OC)=O)([H])C6=C1C(C7=C(O)C=C(C)C=C7O6)=O)=O |
| 分子式 | C30H24O12 |
| 分子量 | 576.5 |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 µg/ml, respectively).1 1.Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016)
2.Kong, F., and Carter, G.T.Remisporine B, a novel dimeric chromenone derived from spontaneous Diels-Alder reaction of remisporine ATetrahedron Lett.44(15)3119-3122(2003) |
