| CAS: | 1353867-91-0 |
| 分子式: | C16H16F3N5 |
| 分子量: | 335.33 |
| 纯度: | >98% |
| 溶解性: | DMSO |
| 存储: | 4℃, protect from light In solvent : -80℃, 6 months; -20℃, 1 month (protect from light) |
| 研究领域: | Cancer |
| Target: | IC50: 5.6 μM (CKIα);8.8 μM (CKIδ);29 μM (CDK7);52 μM (ERK2)[1] |
| 描述: | Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. Longdaysin inhibits CK1α, CK1δ, CDK7, and ERK2. |